It is possible to do a simple analysis of regions-of-interest (ROI’s) with LVis. Although LVis is usually used as a GUI for ORTEC’s GammaVision software, GammaVision is not needed for ROI analyses and LVis can calculate the results on its own. To do that, it is only necessary to install ORTEC’s hardware driver package ”Connections”. A ROI measurement is saved as an LVM file very similar to the LVM files used when working with GammaVision. In fact, it is possible to combine a GammaVision analysis and a ROI analysis in one LVM file. If an acquisition will be evaluated with GammaVision, ROI analysis or both is decided when creating a counting routine (defining a parameter set).